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Classification of single-trial neural responses to cutaneous stimulation
Conference proceeding

Classification of single-trial neural responses to cutaneous stimulation

G Foffani, B Tutunculuer and K.A Moxon
Proceedings of the 25th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (IEEE Cat. No.03CH37439), v 3, pp 2144-2146 Vol.3
2003

Abstract

Biomedical engineering Computational efficiency Electrodes Histograms Linear discriminant analysis Neurons Plasma welding Principal component analysis Sensor arrays Testing
Given the response of a population of neurons to a set of stimuli (or events), classification methods have been used to determine which stimulus generated the response on a single-trial basis. Various linear and non-linear methods have been used to solve this classification problem with surprising little performance differences. We therefore developed a PSTH-based classification method with the aim of maximizing computational efficiency rather than classification performance. This method was tested by applying it to populations of neurons simultaneously recorded from the somatosensory cortex of the rat during cutaneous stimulation of the forepaw and the results were compared to linear discriminant analysis (LDA), which has been considered the "standard". This method performs at least as well as LDA and it is particularly efficient for complete cross-validation designs.

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Web of Science research areas
Cardiac & Cardiovascular Systems
Computer Science, Interdisciplinary Applications
Engineering, Biomedical
Medicine, Research & Experimental
Neurosciences
Radiology, Nuclear Medicine & Medical Imaging
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