Conference proceeding
Comparative study of anti acne activity in two varieties of genus Achillea
Planta Medica, v 80(10)
14 Jul 2014
Abstract
Acne vulgaris is a common disorder especially seen on the onset of adulthood, affecting an estimated 80 – 90% of teenagers. The search for plant based remedies for the treatment of this disease has always been of interest to cosmetic science since the prolonged use of antibiotics has created a problem of antibiotic resistance amongst the acne inducing bacteria,
Propionibacterium acnes
and
Staphylococcus epidemidis
. Extracts of two varieties of genus
Achillea
viz. a cultivar
A. millefolium
'Moonshine' and
A. millefolium
var.
millefolium
obtained from United States and India respectively were tested for their anti acne properties.
Lowest Minimum Inhibitory Concentration (MIC) for the antimicrobial activity against the two acne causing organisms,
P. acnes
and
S.epidermidis
were established for extracts in different solvents. The MIC for petroleum ether extract of Moonshine variety against
S. epidermidis
and the ethyl acetate extract of
millefolium
variety against
P.acnes
were found to be the best. The petroleum ether extract of both varieties also showed potent free radical scavenging and anti tyrosinase activity which determines the ability to remove residual pigmentation on skin. Phytochemical screening of the most potent extract for both plants will be carried out for identification and characterization of anti-acne compounds present. These results will help to establish a comparative study of the anti acne potentials between the two plants and provide data on recommendations of a possible combination of the two varieties for a stronger anti-acne effect.
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Details
- Title
- Comparative study of anti acne activity in two varieties of genus Achillea
- Creators
- R Shah - University of the SciencesA Patel - University of the SciencesB Peethambaran - University of the SciencesM Shah - Department of Pharmacognosy, L.M. College of Pharmacy, India
- Publication Details
- Planta Medica, v 80(10)
- Conference
- American Society of Pharmacognosy 2014 Annual Meeting, held in conjunction with the 14th Annual Oxford International Conference on the Science of Botanicals (Oxford, Mississippi, United States, 2014)
- Publisher
- Thieme
- Resource Type
- Conference proceeding
- Language
- English
- Academic Unit
- Radiation Oncology (and Nuclear Medicine)
- Other Identifier
- 991019170469504721