Conference proceeding
Differential gating of somatosensory input during active and passive stimulation
MEMORY AND EMOTION, v 12, pp 163-180
01 Jan 2002
Abstract
Computational modeling combined with multiple, simultaneously recorded single units in the rat somatosensory system was used to study the modulation of sensory information by 1) ascending noradrenergic afferents and 2) descending cortical projections. Noradrenergic afferents participate in the control of processes such as arousal and alerting by modulating the state of the network. The transition to more aroused states is associated with an increase in norepinephrine activity. In addition to this noradrenergic modulation, coritco-fugal descending projections modulate the size and shape of receptive fields. Our computational model explored the mechanisms underlying these phenomena. Results showed that norepinephrine transitions the network from a non-relay oscillatory state to a relay mode associated with tonic activity. Corticofugal descending projections, during passive tactile stimulation, initiate development of long latency responses and shifted receptive fields. The model also explored the role of these phenomena during active tactile exploration.
Metrics
15 Record Views
Details
- Title
- Differential gating of somatosensory input during active and passive stimulation
- Creators
- K A MoxonS LeiserR MarkowitzJ K Chapin
- Contributors
- P Calabrese (Editor)A Neugebauer (Editor)
- Publication Details
- MEMORY AND EMOTION, v 12, pp 163-180
- Series
- SERIES ON BIOPHYSICS AND BIOCYBERNETICS
- Publisher
- World Scientific
- Number of pages
- 18
- Resource Type
- Conference proceeding
- Language
- English
- Academic Unit
- School of Biomedical Engineering, Science, and Health Systems
- Web of Science ID
- WOS:000181288800014
- Other Identifier
- 991019168391904721
InCites Highlights
Data related to this publication, from InCites Benchmarking & Analytics tool:
- Web of Science research areas
- Neurosciences
- Psychology