Conference proceeding
Dynamic light scattering as an objective noninvasive method in veterinary ophthalmic diagnosis and research
Proceedings of SPIE, Vol.3590(1), pp.361-368
22 Jun 1999
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
The absence of verbal feedback, available from most human patients, is a major limitation in veterinary diagnosis in general and in the evaluation of ophthalmic lens opacity in particular. A novel compact dynamic light scattering (DLS) instrument, developed at NASA, offers significant mitigation to this limitation. It not only yields objective repeatable non-invasive estimation of lens opacity but also provides insight into the nature of chemical and physical alternations in the lens and other eye structures. For example, DLS measurements of the cataractous lens may be interpreted in terms of alpha crystalline protein size. In contrast to most conventional methods, the examination results are numerical and readily accommodate statistical analysis. We present results of DLS measurements in laboratory rabbits with naphthalene induced cataracts, rodents with genetically conditioned hypertension and/or diabetes mellitus; as well as applications of the DLS method in clinical veterinary patients. Use of DLS in examination of phacoemulsification fluid, urine and other biological materials, and potential applications in ocular toxically will also be discussed.
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Details
- Title
- Dynamic light scattering as an objective noninvasive method in veterinary ophthalmic diagnosis and research
- Creators
- Stephen Dubin - Drexel UniversityRafat R Ansari - Glenn Research CenterOrien Tulp - Drexel UniversitySheldon Steinberg - University of PennsylvaniaSeth Koch - University of PennsylvaniaMichael A DellaVecchia - Drexel UniversityMihaela Cozmi - Drexel UniversityMary Victor - Drexel University
- Publication Details
- Proceedings of SPIE, Vol.3590(1), pp.361-368
- Conference
- Lasers in Surgery: Advanced Characterization, Therapeutics, and Systems IX, 9th
- Publisher
- Society of Photo-Optical Instrumentation Engineers (SPIE)
- Resource Type
- Conference proceeding
- Language
- English
- Academic Unit
- [Retired Faculty]
- Identifiers
- 991019167342804721
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InCites Highlights
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- Web of Science research areas
- Cardiac & Cardiovascular Systems
- Dermatology
- Gastroenterology & Hepatology
- Optics
- Otorhinolaryngology
- Surgery
- Urology & Nephrology
- Veterinary Sciences