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Effects of hydrogel properties and extrusion parameters on 3D bioprinting
Conference proceeding

Effects of hydrogel properties and extrusion parameters on 3D bioprinting

Nathan Tessema Ersumo, Kara L Spiller and IEEE
2015 41st Annual Northeast Biomedical Engineering Conference (NEBEC), pp 1-2
Apr 2015

Abstract

Analysis of variance Feeds Image resolution Printing Stress Three-dimensional displays Tissue engineering
In recent years, advances in tissue engineering have brought about the development of 3D bioprinting. By encapsulating cells within a biomaterial for three-dimensional extrusion, this efficient and integrated biofabrication method overcomes the limitations of two-dimensional cell culture, allows for the study of complex cell interactions in a physiologically relevant microenvironment and is a promising stepping stone to the functional replacement of lost or damaged tissue. Despite efforts to improve the cytocompatibility of the extruded biomaterial and to induce specific tissue formation upon extrusion, the effects of hydrogel properties on the extruded construct have been poorly characterized. Here, we assess the impact of various parameters, including biomaterial composition, computer-designed structure and printing speed, on the structural integrity, stress distribution and resolution of the extruded construct.

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Web of Science research areas
Engineering, Biomedical
Engineering, Electrical & Electronic
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