Conference proceeding
Investigating sources of axonal calcium in neuronal cultures modeling Traumatic Brain Injury
2015 41st Annual Northeast Biomedical Engineering Conference (NEBEC), pp 1-2
Apr 2015
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Increased axonal calcium is a common consequence of Traumatic Brain Injuries (TBIs). Understanding the source of this calcium is important to understanding the injury pathway and developing effective therapies. Here we make calcium measurements in live cells after perturbing pieces of the hypothesized TBI pathway, including inducing membrane damage, mitochondrial dysfunction, and increased oxidative stress. The findings provide evidence for dual sources of calcium, both from extracellular influx and intracellular release.
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Details
- Title
- Investigating sources of axonal calcium in neuronal cultures modeling Traumatic Brain Injury
- Creators
- R. M Dastgheyb - Drexel UniversityK. A Barbee - Drexel UniversityG Gallo - Temple UniversityIEEE
- Publication Details
- 2015 41st Annual Northeast Biomedical Engineering Conference (NEBEC), pp 1-2
- Conference
- 2015 41st Annual Northeast Biomedical Engineering Conference (NEBEC), 41st
- Publisher
- IEEE
- Number of pages
- 1
- Resource Type
- Conference proceeding
- Language
- English
- Academic Unit
- School of Biomedical Engineering, Science, and Health Systems
- Web of Science ID
- WOS:000370977700114
- Scopus ID
- 2-s2.0-84941033452
- Other Identifier
- 991019170476804721
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- Collaboration types
- Domestic collaboration
- Web of Science research areas
- Engineering, Biomedical
- Engineering, Electrical & Electronic