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Leporine model refinement for investigation of an ophthalmic dynamic light scattering instrument
Conference proceeding

Leporine model refinement for investigation of an ophthalmic dynamic light scattering instrument

S Dubin, R.R Ansari, M Victor, S Koch, S Steinberg, T VanWinkel and M Della Vecchia
Proceedings of the IEEE 24th Annual Northeast Bioengineering Conference (Cat. No.98CH36210)
1998

Abstract

Animals Biomedical monitoring Humans Instruments Lenses Light scattering Medical diagnostic imaging NASA Rabbits Testing
Evaluation of lens opacity is indispensable in human clinical monitoring as well as research. The rapid evolution of ophthalmic instrumentation impels the development of models which are anatomically and physiologically realistic; and, at the same time, minimally intrusive to the nonhuman animal subjects. Use of an appropriate dosage regimen and other technical refinements for administration of naphthalene in the rabbit can reliably cause lens opacity and chorioretinal changes with much diminished danger or distress.

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Web of Science research areas
Engineering, Biomedical
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