Conference proceeding
Mechanical Properties of Hydrogel Composites with Carbon Nanobrushes for Tissue Engineering Applications
2013 39th Annual Northeast Bioengineering Conference, 6574484
Apr 2013
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Poloxamer gels have shown promise for repair and regeneration of tissues. Electrically conductive gels can be created by suspending carbon nanobrushes (CNB) in poloxamer gels. These biocompatible gels can support cell proliferation and have wound healing applications. The objective of this work is to optimize gels and mechanically characterize them using rheometry. Poloxamer gels were made using water and Dulbecco's Modified Eagle Medium (DMEM). Carbon nanobrushes were added in different concentrations. Temperature, frequency, and squeeze/pull-off tests were conducted on gels. Results indicate that the elastic and viscous properties of poloxamer gels change when carbon nanobrushes are added. Carbon nanobrushes impart conductivity, introduce nanostructure, and can be utilized to tune the macroscopic mechanical properties of poloxamer gels. Ongoing work will optimize poloxamer content and carbon nanobrush concentration for cell growth. This work is applicable for tissue engineering and regeneration in clinical medicine.
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Details
- Title
- Mechanical Properties of Hydrogel Composites with Carbon Nanobrushes for Tissue Engineering Applications
- Creators
- Carolina Ragolta - Harvard UniversityWilliam H. Marks - Harvard UniversitySze C. Yang - University of Rhode IslandGeorge W. Dombi - University of Rhode IslandSujata K. Bhatia - Harvard UniversityIEEE
- Publication Details
- 2013 39th Annual Northeast Bioengineering Conference, 6574484
- Publisher
- IEEE
- Resource Type
- Conference proceeding
- Language
- English
- Academic Unit
- Microbiology and Immunology
- Web of Science ID
- WOS:000332455300158
- Scopus ID
- 2-s2.0-84887011108
- Other Identifier
- 991021229896404721
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- Collaboration types
- Domestic collaboration
- Web of Science research areas
- Engineering, Biomedical
- Engineering, Electrical & Electronic