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Model of upper airway flow restriction in children with obstructive sleep APNEA
Conference proceeding

Model of upper airway flow restriction in children with obstructive sleep APNEA

D.M Wootton, A Guez, P Vaidyanathan, D Avinash, J.R Stablum, J.M McDonough, J.K Udupa and R Arens
2003 IEEE 29th Annual Proceedings of Bioengineering Conference, v 2003-
2003

Abstract

Anatomy Computational fluid dynamics Fluid flow control Image processing Image segmentation Immune system Magnetic resonance imaging Pediatrics Pressure control Sleep apnea
Obstructive sleep apnea syndrome (OSAS) in children is correlated to anatomy of the upper airway. Segmented magnetic resonance images of airways from ten OSAS and ten matched control children were used to generate computer flow models. Steady turbulent axisymmetric flow models were solved at peak flow rate to estimate the effect of restricted airway area on pressure drop and resistance. OSAS patients had significantly higher pressure drop and resistance than controls. The magnitude of pressure drop was similar to reported critical airway closure pressures. A subset of OSAS patients had pressure drop and flow resistance similar to controls. Flow modeling may be a useful method to assess the role of anatomy in OSAS.

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Web of Science research areas
Computer Science, Artificial Intelligence
Engineering, Biomedical
Instruments & Instrumentation
Radiology, Nuclear Medicine & Medical Imaging
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