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Monitoring diabetic wound healing by NIR spectroscopy
Conference proceeding

Monitoring diabetic wound healing by NIR spectroscopy

Elisabeth S. Papazoglou, Leonid Zubkov, Linda Zhu, Michael S. Weingarten, Sorn Tyagi, Kambiz Pourrezaei and IEEE
2005 27th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, Vols 1-7, v 7, pp 6662-6664
01 Jan 2005
PMID: 17281800

Abstract

Engineering Engineering, Biomedical Science & Technology Technology
Chronic wounds represent one of the most serious complications of diabetes. Lack of quantitative assessment of healing progress makes diabetic wound management a clinical challenge. We constructed an optical device based on near infrared diffuse optical spectroscopy and monitored the change in wound optical properties during heating. A single source, four detector frequency domain instrument with multiple wavelengths was employed in a streptozotocin induced diabetic rat animal model. Optical properties including absorption and reduced scattering coefficients were measured. Our results show that there is significant difference in the absorption and reduced scattering coefficient of the wounds between diabetic and controls rats, and such difference persists throughout the healing period. Our technique would be highly useful in monitoring and quantifying the wound healing process.

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12 citations in Scopus

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Web of Science research areas
Engineering, Biomedical
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