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Multimodal Polymeric Contrast Agents
Conference proceeding

Multimodal Polymeric Contrast Agents

Nutte Tarn Teraphongphom, Margaret A Wheatley, Peter Chhour, David P Cormode and IEEE
2013 39th Annual Northeast Bioengineering Conference
Apr 2013
DOI: https://doi.org/10.1109/NEBEC.2013.114
Featured in Collection :   UN Sustainable Development Goals @ Drexel

Abstract

In vitro Magnetic Iron Oxide Magnetic resonance imaging Magnetoacoustic effects Microbubble Multimodal Nanoparticle Programmable logic arrays Quantum Dots Scanning electron microscopy Surface morphology Ultrasound Contrast Agent
Ultrasound Contrast Agents (UCA) are microencapsulated gas bubbles used to increase the overall contrast of the ultrasound (US) image. Novel multimodal polymeric UCA containing additional contrast agents that are active in multiple imaging modalities have been developed. Three platforms of loaded poly (lactic acid) (PLA) shelled UCA are presented. The first two platforms co-encapsulate aqueous or organic Quantum Dots (QD). The Third platform contains magnetic iron oxide nanoparticles (MNP). All platforms showed that the properties of UCA are maintained as well as the properties of additional encapsulated contrast agent. This study explores the potential application for improving the screening of a subject using at least two different modalities, e.g. ultrasound and magnetic resonance imaging.

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#3 Good Health and Well-Being

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Collaboration types
Domestic collaboration
Web of Science research areas
Engineering, Biomedical
Engineering, Electrical & Electronic
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