Conference proceeding
Nanomanipulation and characterization of structural proteins
PROCEEDINGS OF THE 26TH ANNUAL INTERNATIONAL CONFERENCE OF THE IEEE ENGINEERING IN MEDICINE AND BIOLOGY SOCIETY, VOLS 1-7, Vol.26, pp.2582-2583
PROCEEDINGS OF ANNUAL INTERNATIONAL CONFERENCE OF THE IEEE ENGINEERING IN MEDICINE AND BIOLOGY SOCIETY
01 Jan 2004
PMID: 17270802
Abstract
A methodology is presented for simultaneous mechanical testing and atomic force microscopy imaging of single collagen fibrils under load. This method holds the promise for determining single-fibril modulus and strength in various experimental preparations. Examples of this utility include characterization of deformation and failure modes of naturally occurring and engineered structural proteins. Additional promise of this technique is robotic surgery at the sub-micron scale for repairing neuronal tracts and capillaries with structural proteins. A series of algorithms for tying knots at the nanoscale in single fibrils is also presented.
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Details
- Title
- Nanomanipulation and characterization of structural proteins
- Creators
- B E LaytonR GuptaN L JacksonA J ShahR E StallcupS M Sullivanieee
- Publication Details
- PROCEEDINGS OF THE 26TH ANNUAL INTERNATIONAL CONFERENCE OF THE IEEE ENGINEERING IN MEDICINE AND BIOLOGY SOCIETY, VOLS 1-7, Vol.26, pp.2582-2583
- Series
- PROCEEDINGS OF ANNUAL INTERNATIONAL CONFERENCE OF THE IEEE ENGINEERING IN MEDICINE AND BIOLOGY SOCIETY
- Publisher
- IEEE
- Number of pages
- 2
- Resource Type
- Conference proceeding
- Language
- English
- Academic Unit
- Pharmacology and Physiology
- Identifiers
- 991019167788404721
InCites Highlights
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- Web of Science research areas
- Computer Science, Interdisciplinary Applications
- Engineering, Biomedical
- Engineering, Multidisciplinary
- Medicine, Research & Experimental
- Neurosciences
- Radiology, Nuclear Medicine & Medical Imaging