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Numerical Simulations of Capillary Electrokinetic Pinched Injection Separation Flows in Microchannels
Conference proceeding

Numerical Simulations of Capillary Electrokinetic Pinched Injection Separation Flows in Microchannels

Bakhtier Farouk and Fang Yan
Fluids Engineering, v 260, pp 309-318
01 Jan 2004

Abstract

Numerical simulations were performed to study the capillary electrokinetic flow in microchannels. A sample stream consisting of three different species is focused during the loading step and driven into a separation channel during the dispensing step. Flow fields and species distributions are simulated for both the loading and the dispensing steps in a two dimensional cross channel device. The evolution of each sample species concentration at the end of the separation channel is predicted. The separation resolution is defined from the sample species concentration band retention time and band width. Different separation performances can be obtained by manipulating the electric field strengths. A series of simulations for different electric field distributions and field magnitudes in the channel are presented. The goal of these simulations is to identify the parameters providing optimal separation performance. The effect of both loading and dispensing schemes on species concentration and separation resolution is presented.

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