Conference proceeding
Peptide surface modification of PLA ultrasound contrast agent for targeting
2003 IEEE 29th Annual Proceedings of Bioengineering Conference, v 2003-
2003
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
REDV and RGD peptide sequences were conjugated to hollow microspheres to develop targeted PLA ultrasound contrast agents that enhance imaging. The microspheres were coated with either RGD or REDV peptide sequences that target integrins active in angiogensis, /spl alpha//sub v//spl beta//sub 3/ and /spl alpha//sub v//spl beta//sub 5/. The microspheres were then shown to bind to human breast carcinoma cells in vitro within 5 minutes. The peptide modified microspheres makes them ideal candidates for targeted imaging.
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Details
- Title
- Peptide surface modification of PLA ultrasound contrast agent for targeting
- Creators
- L.M Leodore - Drexel UniversityJ.D Lathia - Drexel UniversityM.A Wheatley - Drexel University
- Publication Details
- 2003 IEEE 29th Annual Proceedings of Bioengineering Conference, v 2003-
- Publisher
- IEEE
- Resource Type
- Conference proceeding
- Language
- English
- Academic Unit
- School of Biomedical Engineering, Science, and Health Systems
- Web of Science ID
- WOS:000184414900095
- Other Identifier
- 991019170561804721
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InCites Highlights
Data related to this publication, from InCites Benchmarking & Analytics tool:
- Web of Science research areas
- Computer Science, Artificial Intelligence
- Engineering, Biomedical
- Instruments & Instrumentation
- Radiology, Nuclear Medicine & Medical Imaging