Conference proceeding
Plasma surface modification of three dimensional poly (epsilon-caprolactone) scaffolds for tissue engineering application
PLASMA ASSISTED DECONTAMINATION OF BIOLOGICAL AND CHEMICAL AGENTS
01 Jan 2008
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
In the present study, the effect of oxygen-based plasma treatment on the three dimensional poly (E-caprolactone) (PCL) was analyzed in terms of surface wettability, surface energy, and surface biocompatibility. The surface treatment was carried out for 1, 3, and 5-min durations on three dimensional PCL scaffolds at atmospheric pressure using a radio frequency (RF) plasma treatment system. The solid surface energies of the modified and unmodified PCL scaffolds were calculated by using the Owens-Wendt's method. To examine the effect of oxygen plasma treatment on cell-scaffold interaction, mouse osteoblast cell line (7F2) was used. Oxygen plasma treatment contributed in decreasing the hydrophobicity of PCL for the 1-min treatment. A change in the surface energy from 39.98 mN/m for untreated to 52.54 mN/m for 1-min treated was observed by the increment in the polar component of surface energy. However, with the extended treatment times (3-min, and 5-min), the hydrophilicity, and the surface energy remained unaffected. The highest mouse osteoblast cells proliferation rate was observed for the 1-min treated sample.
Metrics
Details
- Title
- Plasma surface modification of three dimensional poly (epsilon-caprolactone) scaffolds for tissue engineering application
- Creators
- E. D. Yildirim - Drexel Univ, Dept Mech Engn & Mech, Lab Comp Aided Tissue Engn, 3141 Chestnut St,LeBow 239, Philadelphia, PA 19104 USAM. Gandhi - Drexel Univ, Dept Mech Engn & Mech, Lab Comp Aided Tissue Engn, 3141 Chestnut St,LeBow 239, Philadelphia, PA 19104 USAA. Fridman - Drexel University, Mechanical Engineering and MechanicsS. Guceri - Drexel Univ, Dept Mech Engn & Mech, Lab Comp Aided Tissue Engn, 3141 Chestnut St,LeBow 239, Philadelphia, PA 19104 USAW. Sun - Drexel University, Mechanical Engineering and Mechanics
- Publication Details
- PLASMA ASSISTED DECONTAMINATION OF BIOLOGICAL AND CHEMICAL AGENTS
- Series
- NATO Science for Peace and Security Series A-Chemistry and Biology
- Publisher
- Springer Nature
- Number of pages
- 4
- Grant note
- 0427216 / National Science Foundation (NSF)
- Resource Type
- Conference proceeding
- Language
- English
- Academic Unit
- Mechanical Engineering and Mechanics
- Web of Science ID
- WOS:000257859800017
- Scopus ID
- 2-s2.0-65549147148
- Other Identifier
- 991019170459704721
UN Sustainable Development Goals (SDGs)
This publication has contributed to the advancement of the following goals:
InCites Highlights
Data related to this publication, from InCites Benchmarking & Analytics tool:
- Web of Science research areas
- Engineering, Biomedical
- Engineering, Mechanical