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Quantifying focal disruptions in axonal microtubules
Conference proceeding

Quantifying focal disruptions in axonal microtubules

R. M Dastgheyb, K. A Barbee, G Gallo and IEEE
2015 41st Annual Northeast Biomedical Engineering Conference (NEBEC), pp 1-2
Apr 2015

Abstract

Brain injuries Calcium Electric breakdown MATLAB Nerve fibers
Focal disruptions in axonal microtubules are a common consequence of Traumatic Brain Injuries (TBIs), and the ability to quantify these disruptions is essential to evaluating in vitro injury models and therapies. Here, we develop and implement an algorithm to demonstrate the ability to quantify focal disruptions in the microtubules of cultured neurons. The algorithm is implemented using a combination of ImageJ for pre-processing and Matlab for axon analysis and tubulin breakdown identification.

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Collaboration types
Domestic collaboration
Web of Science research areas
Engineering, Biomedical
Engineering, Electrical & Electronic
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