Conference proceeding
Sensing, Capturing and Interrogation of Single Virus Particles with Solid-State Nanopores
ADVANCES IN GLOBAL HEALTH THROUGH SENSING TECHNOLOGIES 2015, v 9490, pp 94900M-94900M-7
01 Jan 2015
Abstract
Solid-state nanopores have gained much attention as a bioanalytical platform. By virtue of their tunable nanoscale dimensions, nanopore sensors can a spatial resolution that spans a wide range of biological species from a single-molecule to a single virus or microorganism. Several groups have already used solid-state nanopores for tag-free detection of viruses. However, no one has reported use of nanopores to capture a single virus for further interrogation by the electric field inside nanopores. In this paper we will report detection of single HIV-1 particle with solid-state nanopores and demonstrate the ability to trap a single HIV-1 particle on top of a nanopore and force it to squeeze through the pore using an electric field.
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Details
- Title
- Sensing, Capturing and Interrogation of Single Virus Particles with Solid-State Nanopores
- Creators
- Armin Darvish - Drexel UniversityGaurav Goyal - Drexel UniversityMinjun Kim - Drexel Univ, Dept Mech Engn, Philadelphia, PA 19104 USA
- Contributors
- S O Southern (Editor)I R RodriguezChavez (Editor)C Gartner (Editor)J D Stallings (Editor)
- Publication Details
- ADVANCES IN GLOBAL HEALTH THROUGH SENSING TECHNOLOGIES 2015, v 9490, pp 94900M-94900M-7
- Series
- Proceedings of SPIE
- Publisher
- Spie-Int Soc Optical Engineering
- Number of pages
- 7
- Resource Type
- Conference proceeding
- Language
- English
- Academic Unit
- A.J. Drexel Nanomaterials Institute
- Web of Science ID
- WOS:000359480500011
- Scopus ID
- 2-s2.0-84943392214
- Other Identifier
- 991019174123304721
InCites Highlights
Data related to this publication, from InCites Benchmarking & Analytics tool:
- Web of Science research areas
- Engineering, Biomedical
- Optics