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Conference proceeding
Simulation of chemotaxis-based sorting of heterotypic cell populations
2007 IEEE/NIH Life Science Systems and Applications Workshop, pp 249-252
Nov 2007
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Cell sorting is a fundamental process that is involved in early embryo development, tumerogenesis and morphogenesis. The sorting of heterotypic cell populations is produced by a variety of inter-cellular actions, e.g. differential adhesion and motility. We recently developed a software system that simulates chemotaxis-based cell aggregation in 2D. The model implemented within the system includes a variety of physiological cell behaviors, such as chemical diffusion/detection, motility, proliferation, adhesion and life cycle stages. In this paper we extend the model to simulate heterotypic cell sorting. This paper provides an overview of the chemotaxis-based aggregation model and describes the parameters and processes utilized to simulate the sorting of two different cell populations based on chemotactic interactions.
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3 citations in Scopus
Details
- Title
- Simulation of chemotaxis-based sorting of heterotypic cell populations
- Creators
- Manolya Eyiyurekli - Drexel UniversityPeter I Lelkes - Drexel UniversityDavid E Breen - Drexel UniversityIEEE
- Publication Details
- 2007 IEEE/NIH Life Science Systems and Applications Workshop, pp 249-252
- Publisher
- IEEE
- Resource Type
- Conference proceeding
- Language
- English
- Academic Unit
- Computer Science
- Web of Science ID
- WOS:000255229500062
- Scopus ID
- 2-s2.0-50849122016
- Other Identifier
- 991019170608504721
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- Web of Science research areas
- Engineering, Biomedical
- Engineering, Electrical & Electronic