Conference proceeding
Simulations at a newly derived reference model of the human lung
Proceedings of SPIE, v 5318(1), pp 163-169
01 Jul 2004
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Based on an in-vitro preparation of an adult human lung combined with high-resolution tomography we developed a realistic graph representation of the bronchial tree of a particular human lung. The graph contains topological information about spatial coordinates, connectivities, diameters and branching angles of 1453 bronchi up to the 17th Horsfield order, and is characterized by asymmetric and multifractal properties. This geometrical model was the basis for the development of an unstructured, multiphase CFD model of the trachea and upper airways. This is directly relevant to research in that intricate anatomical system geometries are employed. Based on medical imaging data CFD modeling associated with complex moving geometries, multi-phase/multi-species physics, and turbulence is incorporated. We contrast this approach with the use of mass-transport equations that describe the gas transport axially. Results show that many of the transport processes within the airways depend quite sensitively on the geometry of the bronchial bifurcations and the structure of the boundaries.
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Details
- Title
- Simulations at a newly derived reference model of the human lung
- Creators
- Andres Kriete - Drexel UniversityAndreas H Schmidt - University of WürzburgStephan Zidowitz - Fraunhofer MEVISDaniel C Haworth - Pennsylvania State UniversityRobert F Kunz - Pennsylvania State University
- Publication Details
- Proceedings of SPIE, v 5318(1), pp 163-169
- Conference
- Advanced Biomedical and Clinical Diagnostic Systems II (San Jose, California, United States, 24 Jan 2004–29 Jan 2004)
- Publisher
- Society of Photo-Optical Instrumentation Engineers (SPIE)
- Number of pages
- 7
- Resource Type
- Conference proceeding
- Language
- English
- Academic Unit
- School of Biomedical Engineering, Science, and Health Systems
- Web of Science ID
- WOS:000223125300019
- Scopus ID
- 2-s2.0-5744221878
- Other Identifier
- 991019173430904721
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InCites Highlights
Data related to this publication, from InCites Benchmarking & Analytics tool:
- Web of Science research areas
- Engineering, Biomedical
- Imaging Science & Photographic Technology
- Optics