Conference proceeding
Strain measurements in vascular smooth muscle cells grown on a biaxially-stretched substrate
Images of the Twenty-First Century. Proceedings of the Annual International Engineering in Medicine and Biology Society, v 11, pp 864-865
1989
Abstract
Vascular smooth muscle cells were grown on a compliant membrane to which a uniform, biaxial strain was applied. The displacements of cell-surface markers were measured, so that cell strain could be calculated. This system provides the means to measure quantitatively the mechanical response of cells in culture to a controlled mechanical input. The actual deformation of the cells was determined by measuring the distance between cell surface markers in the deformed and undeformed states. It was found that the variation in cell strain is due to morphological and mechanical properties of the cell, such as strength of attachment, degree of spreading, and organization, and stiffness of cytoskeletal elements.< >
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Details
- Title
- Strain measurements in vascular smooth muscle cells grown on a biaxially-stretched substrate
- Creators
- K.A Barbee - University of PennsylvaniaL.E Thibault - University of Pennsylvania
- Publication Details
- Images of the Twenty-First Century. Proceedings of the Annual International Engineering in Medicine and Biology Society, v 11, pp 864-865
- Conference
- Images of the Twenty-First Century. Annual International Engineering in Medicine and Biology Society
- Publisher
- IEEE
- Number of pages
- 1
- Resource Type
- Conference proceeding
- Language
- English
- Academic Unit
- School of Biomedical Engineering, Science, and Health Systems
- Web of Science ID
- WOS:A1989BQ05S00437
- Other Identifier
- 991019231656104721
InCites Highlights
Data related to this publication, from InCites Benchmarking & Analytics tool:
- Web of Science research areas
- Engineering, Biomedical
- Instruments & Instrumentation