Conference proceeding
Structural Assessment of a Tissue Engineered Scaffold for Bone Repair
Illumina Technology Records - unstructured
01 Jan 2001
Abstract
The limitations of current grafting materials have driven the search for synthetic alternatives to cancellous bone. A variety of biodegradable polymer foams composed of poly(lactide-co-glycolide) PLAGA have been evaluated for such uses. However, structural limitations may restrict the clinical use of these scaffolds. We have developed a sintered microsphere scaffold composed of 85:15 poly(lactide-co-glycolide) with a biommetic pore system equivalent to the structure of cancellous bone. Analysis of the structural data, indicated that the microsphere matrix sintered at a temperature of 160 degrees C with a microsphere diameter of 355-425 micrometer resulted in a optimal, biomimetic structure with an approximate pore diameter of 75 to 275 micrometer, 35
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Details
- Title
- Structural Assessment of a Tissue Engineered Scaffold for Bone Repair
- Creators
- Cato LaurencinMark BordenMohamed AttawiaSaadig El-Amin
- Publication Details
- Illumina Technology Records - unstructured
- Resource Type
- Conference proceeding
- Language
- English
- Identifiers
- 991019339565704721