Conference proceeding
Synthetic Nanoscale Architectures for Lipoprotein Separation
Volume 13: Nano-Manufacturing Technology; and Micro and Nano Systems, Parts A and B, v 13, pp 825-829
01 Jan 2008
Abstract
Current low density lipoprotein (LDL) apheresis procedures are expensive and time consuming. We report here a novel technique to detect and separate nanoparticles using solid state nanopores. Our technique relies on the resistive pulse phenomenon used in coulter counters. We used a 150nm diameter nanopore to detect nanoparticles that closely resembled HDL and LDL in terms of their size and surface charge. Statistical analysis of the translocation data revealed that our setup preferentially allowed the particles resembling HDL to pass thorough while restricting the translocation of the particles that resembled LDL.
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Details
- Title
- Synthetic Nanoscale Architectures for Lipoprotein Separation
- Creators
- Anmiv S Prabhu - Drexel UniversityAlejandro Moraga - Drexel UniversityMichael Cecchini - Drexel UniversityRafael Mulero - Drexel UniversityStephen Olsen - Drexel UniversityYoung I Cho - Drexel UniversityMin Jun Kim - Drexel UniversityASME
- Publication Details
- Volume 13: Nano-Manufacturing Technology; and Micro and Nano Systems, Parts A and B, v 13, pp 825-829
- Conference
- ASME 2008 International Mechanical Engineering Congress and Exposition (Boston, Massachusetts, United States, 31 Oct 2008–06 Nov 2008)
- Publisher
- ASMEDC
- Resource Type
- Conference proceeding
- Language
- English
- Academic Unit
- Mechanical Engineering and Mechanics
- Web of Science ID
- WOS:000266546900106
- Scopus ID
- 2-s2.0-70049083866
- Other Identifier
- 991019170472604721
InCites Highlights
Data related to this publication, from InCites Benchmarking & Analytics tool:
- Web of Science research areas
- Engineering, Mechanical
- Nanoscience & Nanotechnology