Conference proceeding
Translational Potential for Hydrogel Composites Containing Carbon Nanobrushes
2012 38TH ANNUAL NORTHEAST BIOENGINEERING CONFERENCE (NEBEC), pp 392-393
01 Jan 2012
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
The objective of this work is to examine potential translational directions for electrically conductive hydrogel composites as a matrix for clinically relevant cell lines. The composite is comprised of carbon nanobrushes embedded in a biocompatible poloxamer gel. This work assesses the ability of such composite gels to support the growth of fibroblasts and myocytes and eventually serve as a matrix to stimulate wound closure. In such a model, fibroblasts and myocytes are seeded on the hydrogel and bathed in culture medium. The experimental model assesses the ability of fibroblasts and myocytes to grow into and adhere to the gel. The work demonstrates that carbon nanobrushes can be dispersed within poloxamer gels, and that fibroblasts and myocytes can proliferate within homogenously dispersed carbon nanobrush-containing poloxamer gels. Future work will examine the effects of design parameters such as carbon nanobrush content and matrix structure on wound healing, as well as the growth of tendons and other cell lines within the hydrogel composites. This work has relevance for tissue engineering and tissue regeneration in clinical medicine.
Metrics
Details
- Title
- Translational Potential for Hydrogel Composites Containing Carbon Nanobrushes
- Creators
- William H. Marks - Harvard UniversitySze C. Yang - University of Rhode IslandGeorge W. Dombi - University of Rhode IslandSujata K. Bhatia - Harvard UniversityIEEE
- Publication Details
- 2012 38TH ANNUAL NORTHEAST BIOENGINEERING CONFERENCE (NEBEC), pp 392-393
- Series
- Annual IEEE Northeast Bioengineering Conference
- Publisher
- IEEE
- Number of pages
- 2
- Resource Type
- Conference proceeding
- Language
- English
- Academic Unit
- Microbiology and Immunology
- Web of Science ID
- WOS:000309001200196
- Scopus ID
- 2-s2.0-84862739889
- Other Identifier
- 991021229902804721
UN Sustainable Development Goals (SDGs)
This publication has contributed to the advancement of the following goals:
InCites Highlights
Data related to this publication, from InCites Benchmarking & Analytics tool:
- Collaboration types
- Domestic collaboration
- Web of Science research areas
- Engineering, Biomedical
- Engineering, Electrical & Electronic