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Unit cell analysis and characterization of three-dimensional two-phase tissue scaffolds
Conference proceeding

Unit cell analysis and characterization of three-dimensional two-phase tissue scaffolds

C Gomez, M.F Demirci, W Sun, A Shokoufandeh and IEEE
Proceedings of the IEEE 31st Annual Northeast Bioengineering Conference, 2005, pp 166-167
2005
DOI: https://doi.org/10.1109/NEBC.2005.1431975
Featured in Collection :   UN Sustainable Development Goals @ Drexel

Abstract

Assembly Biodegradable materials Biological materials Biological tissues Cells (biology) Computer architecture Fabrication Informatics Mechanical factors Tissue engineering
Three-dimensional (3D) porous tissue scaffolds are being engineered to promote cell attachment, cell proliferation and functioning heterogeneous tissue formation. A scaffold's structure and transport capabilities need to mimic cells' natural geometrical and architectural environment and will need to consistently provide a flux throughout the scaffold to deliver materials for growth and waste removal. This paper presents our work on establishing a connectivity characterization of designed unit cell tissue structures for surface alignment between units to insure both geometric connectivity and mass and fluid transport within a heterogeneous tissue scaffold to meet both structural and biological requirements for cell growth and tissue growth. To capture this information, skeletal representations of the unit cell structures have been utilized for subsequent assembly processes.

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Web of Science research areas
Engineering, Biomedical
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