Conference proceeding
Unitary premotor drives and modular reflex primitives in frog spinal cord
Proceedings of the 25th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (IEEE Cat. No.03CH37439), v 4, pp 3843-3845 Vol.4
2003
Abstract
Modular organization of reflexes and premotor drives in frog spinal cord can be revealed in a number of ways. Isometric force-field measurements, electromyogram decomposition with statistical methods, and direct reflex manipulation all support a small number of elements supporting spinal behaviors. The central neural circuits that support the modules indicated by these methods are not well understood. A current focus of our laboratory is to begin to examine activity patterns that support modular common drives. To examine activity we are using a Bionic Technologies Cerebus 128 channel system with real time (1KHz 1ms resolution) delivery of up to 2 resolved spikes spikes per channel. Neuralynx Cyborg drives, microwire, and tetrodes are being tested for recording with this system. Activity is elicited by reflex stimulation to induce wipe movements or muscle vibration. We are also testing activity induction by photolytic uncaging of glutamate in the preparation, a technique with the advantage of no electrical artefact but perhaps reduced temporal precision. If recruited by microstimulation or other means a modular spinal circuitry may in the future support powerful neuroprosthetic designs.
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Details
- Title
- Unitary premotor drives and modular reflex primitives in frog spinal cord
- Creators
- S.F Giszter - Drexel University
- Publication Details
- Proceedings of the 25th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (IEEE Cat. No.03CH37439), v 4, pp 3843-3845 Vol.4
- Publisher
- IEEE
- Resource Type
- Conference proceeding
- Language
- English
- Academic Unit
- Neurobiology and Anatomy
- Web of Science ID
- WOS:000189395301007
- Other Identifier
- 991019167331504721
InCites Highlights
Data related to this publication, from InCites Benchmarking & Analytics tool:
- Web of Science research areas
- Cardiac & Cardiovascular Systems
- Computer Science, Interdisciplinary Applications
- Engineering, Biomedical
- Medicine, Research & Experimental
- Neurosciences
- Radiology, Nuclear Medicine & Medical Imaging