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PDFOpen Access (License Unspecified), Open Access
Dissertation
FMRI of the cervical spinal cord
Doctor of Philosophy (Ph.D.), Drexel University
2000
DOI:
https://doi.org/10.17918/00008235
Abstract
Extension of fMRI (functional magnetic resonance imaging) beyond its current application in brain studies to imaging of the spinal cord is of great potential value in both basic research and clinical applications. Currently, the choices available for non-invasive clinical study of the human spinal cord are limited and none support the study of its functions. We report on the first successful study which elicits the BOLD (blood oxygenation level dependant) signal within the human cervical spinal cord using gradient echo EPI (echo planar imaging) and 1.5 Tesla echo speed clinical scanner. When subjects performed three different motor tasks, three spatially distinct regions of activity were identified in the spinal cord each motor task. Moreover, there was linear relationship between the amount of applied force and the strength of the BOLD signal.
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Details
- Title
- FMRI of the cervical spinal cord
- Creators
- Saaussan Madi
- Contributors
- Jonathan Nissanov (Advisor) - Drexel University, Drexel University (1970-)
- Awarding Institution
- Drexel University
- Degree Awarded
- Doctor of Philosophy (Ph.D.)
- Publisher
- Drexel University; Philadelphia, Pennsylvania
- Number of pages
- vii, 120 pages
- Resource Type
- Dissertation
- Language
- English
- Academic Unit
- School of Biomedical Engineering, Science, and Health Systems (1997-2026); Drexel University
- Other Identifier
- 991021889007404721