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Multiplex network analysis of local topology in simulated and in vitro spiking neural networks
Dissertation   Open access

Multiplex network analysis of local topology in simulated and in vitro spiking neural networks

Myles Akin
Doctor of Philosophy (Ph.D.), Drexel University
Jun 2018
DOI:
https://doi.org/10.17918/D8CM1D
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Abstract

Neurosciences Neural networks (Computer science) Neural networks (Computer science)--Mathematics Applied Mathematics Mathematics
Complex networks are important tools for investigating interactions amongst many different types of agents. Recently, the extension of single layer networks to multilayer networks has allowed for multiple types of relationships among the same actors to be represented in a network. In this dissertation, we develop two methods for using a specific type of multilayer network, the multiplex network, to study local topology in neural networks. In the first project, we use multiplex networks to compare the local topology between a simulated structural neural network and its inferred functional networks. For the second project, we use multiplex networks to observe evidence for the self-organization of in vitro neural networks into neural ensembles.

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