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Numerical methods and uniquness for the Canham-Helfrich model of biomembranes
Dissertation   Open access

Numerical methods and uniquness for the Canham-Helfrich model of biomembranes

Jingmin Chen
Doctor of Philosophy (Ph.D.), Drexel University
01 May 2015
DOI:
https://doi.org/10.17918/etd-6330
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Abstract

Membranes (Biology) Canham-Helfrich Model Mathematics
The classical Canham-Helfrich models of biomembranes consist of a family of geometric constrained variational problems. Their physical importance and mathematical challenge attract the attention of both biophysicists and geometric analysts. In this PhD thesis, we develop a numerical method for these models. Our method uses a high-order approximation of surfaces with arbitrary topology based on subdivision methods. We also develop multiscale and parallel versions of our method which substantially speed up computations. An implementation based on Matlab and CUDA is provided along with this thesis. We use our solver to explore a phenomenon known as conformal diusion in the biophysical literature, which is also connected to the open uniqueness question for the Canham and Helfrich variation problems. We establish the uniqueness of solution of the Canham problem in a special case related to the Willmore conjecture (now the Marques-Neves theorem).

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