Dissertation
Phosphorescence lifetime imaging in turbid media
Doctor of Philosophy (Ph.D.), Drexel University
Dec 2002
DOI:
https://doi.org/10.17918/etd-81
Abstract
In this dissertation we explore the use of highly scattered photons in an analog of conventional emission tomography. Through this technique we quantitatively reconstruct images of the spatial distribution of oxygen in turbid media. We begin with the mathematical description of diffusive light propagation in highly scattering systems and solve the forward problem. Numerical methods by which the forward problem is inverted are introduced next, enabling quantitative spatial image reconstruction. Then, we present experimental validation of developed techniques, demonstrating quantitative reconstruction of phosphorescence lifetime in highly scattering media.
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Details
- Title
- Phosphorescence lifetime imaging in turbid media
- Creators
- Vadim Soloviev - DU
- Contributors
- Anthony Paul Curatola (Advisor) - Drexel University, Accounting
- Awarding Institution
- Drexel University
- Degree Awarded
- Doctor of Philosophy (Ph.D.)
- Publisher
- Drexel University; Philadelphia, Pennsylvania
- Resource Type
- Dissertation
- Language
- English
- Academic Unit
- College of Arts and Sciences; Drexel University; Mathematics
- Other Identifier
- 81; 991014632835504721