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Dissertation
Prediction of the trabecular architecture and its potential variation (remodeling) on the glenoid of the glenohumeral (GH) joint
Doctor of Philosophy (Ph.D.), Drexel University
Nov 2004
DOI:
https://doi.org/10.17918/etd-365
Abstract
There is little information on bone remodeling and morphology as it relates to the shoulder and that which is available pertains primarily to healthy bone. This study attempted to predict the variation in trabecular architectural remodeling with alterations in the loading conditions acting on the glenoid. This study assumes the validity of Wolff's Law. Three different protocols were used. Protocol 1 investigated the material and morphological characteristics of the glenoid by analyzing eleven computerized tomography datasets and digitized trabecular bone images obtained from twelve cadaver scapula specimens. Protocol 2 used a FEA to compute the principal stress trajectories acting within the glenoid. The principal stresses were derived for five loading conditions, which represent typical functional shoulder activities. The effect of each functional shoulder activity on the formation of the trabecular architecture was then explained by comparing the principal stress trajectories of each activity and the actual trabecular architecture (morphology) obtained from the cadaver specimens. Protocol 3 presented an equation that can predict the trabecular architecture and its potential remodeling, which is determined by comparing the predicted structural changes in the standard trabecular patterns determined for the most common loading condition using the proposed equation. The trabecular architecture is determined from the combination of the cumulative loading time and the loadings that correspond to the shoulder activities. The equation describes these factors after considering the incidence, computed principal stress trajectories, and magnitude of the principal stresses of each activity. The trabecular structure predicted from the equation agreed well with that determined from the cadaver specimens (average deviation angle: 10.5°). The computed trabecular pattern variation under various loading conditions suggests that there is a non-linear relationship between trabecular architecture remodeling and the incidence of a particular shoulder activity. The innovation of the study is that it suggests a new approach for investigating trabecular structure and its remodeling using a combination of trabecular bone images and FEA. The methods developed here may be applicable to a variety of pathological conditions and related orthopedic implants and therapies.
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Details
- Title
- Prediction of the trabecular architecture and its potential variation (remodeling) on the glenoid of the glenohumeral (GH) joint
- Creators
- Dohyung Lim - DU
- Contributors
- Rahamim Seliktar (Advisor) - Drexel University (1970-)
- Awarding Institution
- Drexel University
- Degree Awarded
- Doctor of Philosophy (Ph.D.)
- Publisher
- Drexel University; Philadelphia, Pennsylvania
- Resource Type
- Dissertation
- Language
- English
- Academic Unit
- School of Biomedical Engineering, Science, and Health Systems (1997-2026); Drexel University
- Other Identifier
- 365; 991014632666504721