Dissertation
Sleep disruption and interstitial cystitis symptoms in women
Doctor of Nursing Practice (D.N.P.), Drexel University
Mar 2009
DOI:
https://doi.org/10.17918/etd-3043
Abstract
INTRODUCTION: Interstitial cystitis (IC) is a chronic painful disorder of the bladder of unknown etiology and with no known cure. It affects 1.2 million women in United States. The primary symptoms include urinary frequency, urgency and pain the mean age of diagnosis is 40 years. This disorder has been shown to cause many adverse effects in the lives of people who have it. However there is a gap in literature regarding sleep issues in IC patients and how sleep affects the symptoms of IC. This causes confusion and inconsistencies in treating people with IC and sleep disturbances. The goal of this project was to provide a scientific base for evaluation and treatment of sleep difficulties in this population. METHODS: This cross-sectional descriptive study recruited IC patients (N=407) through the website of the Interstitial Cystitis Association. All subjects completed a web-based questionnaire which included demographic variables, as well as number of years with IC diagnosis, method of diagnosis, type of specialist who made the diagnosis, and menopause status. Depressive symptomswere measured using a single question, and the O'Leary Sant IC Symptom and Problem Index and the Pittsburgh Sleep Quality Index were completed. RESULTS: Most were from the United States, between 56-60 years old and post-menopausal. Also they were predominantly Caucasian and had received a diagnosis of IC at least 10 years ago. Just under half self reported that they were depressed. Mean global PSQI was 13.4 (SD+ 3.64), with 100% of subjects scoring above 5. Results from the linear multiple regression analysis revealed that the predictor variables, nocturia, pain and urgency, were significant predictors of sleep quality, when controlling for age, depression, years with IC and menstrual status (R² = 0.21, p < 0.001). The specific symptoms of IC with the largest relationship with sleep quality were nocturia (r = 0.427, p < 0.001) and pain (r = 0.411, p < 0.001). CONCLUSION: Women with IC have demonstrated poor sleep quality. Nocturia, pain, and urinary urgency contribute 21% of the variance for sleep quality.
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Details
- Title
- Sleep disruption and interstitial cystitis symptoms in women
- Creators
- Alis Kotler Panzera - DU
- Contributors
- Judith Reishtein (Advisor) - Drexel University (1970-)
- Awarding Institution
- Drexel University
- Degree Awarded
- Doctor of Nursing Practice (D.N.P.)
- Publisher
- Drexel University; Philadelphia, Pennsylvania
- Resource Type
- Dissertation
- Language
- English
- Academic Unit
- Doctoral Nursing; Nursing (Graduate); College of Nursing and Health Professions; Drexel University
- Other Identifier
- 3043; 991014632275404721