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Thesis
Characterization of AC electrokinetic effects using pressure-driven flows: a contribution toward the development of lab-on-a-chip applications
Master of Science (M.S.), Drexel University
Mar 2009
DOI:
https://doi.org/10.17918/etd-3004
Abstract
AC electrokinetics is a versatile technique for manipulating particles and fluids for potential use in Lab-on-a-chip applications. However, predicting and analyzing the motion of particles and fluids due to AC electrokinetic effects is a difficult task because it requires the solid combined understanding of multiple phenomena such as Dielectrophoresis, AC Electroosmosis, and Electrothermal Effects. These phenomena have typically been studied individually and little information is available with respect to their combined effects. To study the combined effects, an AC electrokinetic force balance model was proposed and validated as a novel technique to characterize and further enhance the understanding of AC electrokinetic effects. The model is based on net force exerted on a particle due to the interaction between AC electrokinetic effects and external pressure-driven flows. The research presented in this thesis includes the qualitative understanding of the motion of particles due to AC electrokinetic effects without any external forces, and the quantitative understanding of the motion of particles and fluids due to the interaction of AC electrokinetics effects with well-controlled pressure-driven flows. Over the course of the research, simulation and numerous experiments were conducted using 2 [mu]m, 3 [mu]m and 4.6 [mu]m polystyrene particles in various configurations. The experimental and simulation results at various parameter conditions yielded the discovery of several effects critical to the understanding of AC electrokinetic phenomena, in particular AC Electroosmosis. The characterization of AC electrokinetic effects using the AC electrokinetic force model predicted the AC electroosmotic forces acting on the particles and AC electroomotic bulk velocity profiles. These results greatly contribute to the verification and understanding of the area of AC electroosmosis. The use of this model not only allows for the characterization of the AC electrokinetic effects but also can be used to generate qualitative and quantitative results that can lead to techniques toward the development of Lab-on-a-Chip applications. These techniques only await further studies and demonstration and are related to separation, controlled transport, sensing and mixing of particles in the life sciences and biomedical technologies.
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Details
- Title
- Characterization of AC electrokinetic effects using pressure-driven flows
- Creators
- Jorge Jonathan Capurro - DU
- Contributors
- Moses Noh (Advisor) - Drexel University (1970-)
- Awarding Institution
- Drexel University
- Degree Awarded
- Master of Science (M.S.)
- Publisher
- Drexel University; Philadelphia, Pennsylvania
- Resource Type
- Thesis
- Language
- English
- Academic Unit
- College of Engineering (1970-2026); Mechanical Engineering (and Mechanics) [Historical]; Drexel University
- Other Identifier
- 3004; 991014632560804721