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Thesis
Vitamin B₆ in premenstrual syndrome
Master of Science (M.S.), Drexel University
1984
DOI:
https://doi.org/10.17918/00002558
Abstract
Premenstrual syndrome (PMS) is a complex emotional and physical disorder characterized by many symptoms. Numerous hypotheses have been suggested to explain the etiology of premenstrual syndrome; however a unified pathological cause has yet to be determined. The treatment of PMS is aimed at various levels. Vitamin therapy along with dietary modification is currently a widely used treatment in treating this population. The purpose of this research project was to assess if a correlation exists between the reporting of symptoms from women suffering from PMS and Vitamin B₆ status as estimated by stimulation of erythrocyte glutamic oxaloacetate transaminase (EGOT) activity and estimated calculated dietary intake. The differences between the experimental group and the control group were tested before treatment began. The control group significantly reported less severe symptoms but showed a similar EGOT Index compared to the experimental group, Correlations between all of the symptom clusters were positively and statistically significant for the control group as opposed to the experimental group, After the treatment phase, the EGOT Index for both groups improved. Both groups reported less severe symptoms after the treatment phase. A significant correlation was found between symptoms associated with appetite and the second EGOT Index. It appeared that as B₆ levels improved, appetite increased. The nutrient composition of the diets between both groups were marginally different. Both groups revealed only 50% of the RDA for Vitamin B₆ in their diets. Magnesium dietary intake was also found to be low for both groups. Sodium intake for the experimental group sharply decreased after the treatment phase. This research represents one of the first studies to measure Vitamin B₆ levels in women with premenstrual syndrome. Dietary factors also appeared to play an important role in the reporting of symptoms in this study. More studies are needed of longer duration along with double-blind placebo techniques.
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Details
- Title
- Vitamin B₆ in premenstrual syndrome
- Creators
- Michelle Susan Krutan
- Awarding Institution
- Drexel University
- Degree Awarded
- Master of Science (M.S.)
- Publisher
- Drexel University; Philadelphia, Pennsylvania
- Number of pages
- x, 75, [31] pages
- Resource Type
- Thesis
- Language
- English
- Academic Unit
- Drexel University
- Other Identifier
- 991021888067304721