Journal article
125Iodine implantation after lymphadenectomy in early carcinoma of the prostate
International journal of radiation oncology, biology, physics, v 12(12), pp 2117-2125
Dec 1986
PMID: 3793548
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
The interim results of planned lymphadenectomy and 125Iodine implantation for carcinoma of the prostate in 122 patients are reported. The incidence of positive pelvic lymph nodes found at lymphadenectomy ranged from 15% in A-2 to 55% in B-2 lesions, as well as in 13% of well-differentiated tumors. Poorly differentiated histology, B-2 and D-1 tumors, had early treatment failure indicating a group of patients in whom this procedure is contraindicated. Occult disease (A-2) and well-differentiated tumors do not exhibit early failure. However, these patients will also fare well with radical external radiation or prostatectomy. The radiobiology of the low dose rate continuous irradiation of 125Iodine is questioned. It may be inadequate for long-term tumor control. Longer follow-up of this series may indicate that external radiation for clinically localized carcinoma of the prostate is the most effective treatment policy.
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Details
- Title
- 125Iodine implantation after lymphadenectomy in early carcinoma of the prostate
- Creators
- Graeme M. Giles - Glasgow Institute of Radiotherapy and Oncology, ScotlandLuther W. Brady - Hylda Cohn/American Cancer Society Professor of Clinical Oncology; Professor and Chairman, Department of Radiation Oncology and Nuclear Medicine, Hahnemann University, Philadelphia, PA, USA
- Publication Details
- International journal of radiation oncology, biology, physics, v 12(12), pp 2117-2125
- Publisher
- Elsevier
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Radiation Oncology (and Nuclear Medicine)
- Web of Science ID
- WOS:A1986F372400009
- Scopus ID
- 2-s2.0-0022931144
- Other Identifier
- 991019184040104721
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- Collaboration types
- International collaboration
- Web of Science research areas
- Oncology
- Radiology, Nuclear Medicine & Medical Imaging