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16-Year Trends in the Infection Burden for Pacemakers and Implantable Cardioverter-Defibrillators in the United States 1993 to 2008
Journal article   Open access   Peer reviewed

16-Year Trends in the Infection Burden for Pacemakers and Implantable Cardioverter-Defibrillators in the United States 1993 to 2008

Arnold J. Greenspon, Jasmine D. Patel, Edmund Lau, Jorge A. Ochoa, Daniel R. Frisch, Reginald T. Ho, Behzad B. Pavri and Steven M. Kurtz
Journal of the American College of Cardiology, v 58(10), pp 1001-1006
30 Aug 2011
DOI: https://doi.org/10.1016/j.jacc.2011.04.033
PMID: 21867833
Featured in Collection :   UN Sustainable Development Goals @ Drexel
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https://doi.org/10.1016/j.jacc.2011.04.033View
Published, Version of Record (VoR)Open Access (Publisher-Specific),  Open

Abstract

Cardiac & Cardiovascular Systems Cardiovascular System & Cardiology Life Sciences & Biomedicine Science & Technology
Objectives We analyzed the infection burden associated with the implantation of cardiac implantable electrophysiological devices (CIEDs) in the United States for the years 1993 to 2008. Background Recent data suggest that the rate of infection following CIED implantation may be increasing. Methods The Nationwide Inpatient Sample (NIS) discharge records were queried between 1993 and 2008 using the 9th Revision of the International Classification of Diseases (ICD-9-CM). CIED infection was defined as either: 1) ICD-9 code for device-related infection (996.61) and any CIED procedure or removal code; or 2) CIED procedure code along with systemic infection. Patient health profile was evaluated by coding for renal failure, heart failure, respiratory failure, and diabetes mellitus. The infection burden and patient health profile were calculated for each year, and linear regression was used to test for changes over time. Results During the study period (1993 to 2008), the incidence of CIED infection was 1.61%. The annual rate of infections remained constant until 2004, when a marked increase was observed, which coincided with an increase in the incidence of major comorbidities. This was associated with a marked increase in mortality and in-hospital financial charges. Conclusions The infection burden associated with CIED implantation is increasing over time and is associated with prolonged hospital stays and high financial costs. (J Am Coll Cardiol 2011; 58: 1001-6) (C) 2011 by the American College of Cardiology Foundation

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Web of Science research areas
Cardiac & Cardiovascular Systems
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