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Journal article
18F-sodium fluoride: An emerging tracer to assess active vascular microcalcification
Journal of nuclear cardiology, v 28(6), pp 2706-2711
01 Dec 2021
PMID: 32390112
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Visualizing vascular macrocalcification with computed tomography (CT) was the first noninvasive imaging technique to assess atherosclerosis as an alternative to conventional angiography. In 1990, Agatston et al. introduced a method of scoring coronary artery calcification using low-dose CT,1 which subsequently became widely used clinically. Since then, many new modalities such as CT angiography, magnetic resonance image, magnetic resonance angiography, optical coherence tomography, and intravascular ultrasound have provided new insights into plaque morphology such as cap thickness, presence of intraplaque hemorrhage, and presence of a necrotic core. However, because these structural changes occur in later and often irreversible stages of disease, molecular imaging techniques are necessary to characterize early manifestations of atherosclerosis, allowing for timely diagnosis and intervention (Figure 1).
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Details
- Title
- 18F-sodium fluoride: An emerging tracer to assess active vascular microcalcification
- Creators
- William Y. Raynor - Drexel University, Radiology (Radiologic Sciences)Austin J. Borja - Hospital of the University of PennsylvaniaChaitanya Rojulpote - The Wright Center for Graduate Medical EducationPoul Flemming Høilund-Carlsen - Odense University HospitalAbass Alavi - University of Pennsylvania
- Publication Details
- Journal of nuclear cardiology, v 28(6), pp 2706-2711
- Publisher
- Elsevier
- Number of pages
- 6
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Radiology (Radiologic Sciences)
- Web of Science ID
- WOS:000531457400003
- Scopus ID
- 2-s2.0-85084371662
- Other Identifier
- 991019350573804721
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- Collaboration types
- Domestic collaboration
- International collaboration
- Web of Science research areas
- Cardiac & Cardiovascular Systems
- Radiology, Nuclear Medicine & Medical Imaging