Journal article
23Na TQF NMR imaging for the study of spinal disc tissue
Journal of magnetic resonance (1997), Vol.195(1)
2008
PMCID: PMC2796190
PMID: 18774321
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
A method for acquiring triple quantum filtered (TQF)
23Na NMR images is proposed that takes advantage of the differences in transverse relaxation rates of sodium to achieve positive intensity, PI, NMR signal. This PITQF imaging sequence has been used to obtain spatially resolved one-dimensional images as a function of the TQF creation time,
τ, for two human spinal disc samples. From the images the different parts of the tissue, nucleus pulposus and annulus fibrosus, can be clearly distinguished based on their signal intensity and creation time profiles. These results establish the feasibility of
23Na TQF imaging and demonstrate that this method should be applicable for studying human disc tissues as well as spinal disc degeneration.
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Details
- Title
- 23Na TQF NMR imaging for the study of spinal disc tissue
- Creators
- Kristopher J Ooms - Department of Chemistry and Biochemistry, University of Delaware, 036 Brown Laboratories, Newark, 19716 DE, USAMarco Cannella - Department of Materials Science and Engineering, Drexel University, LeBow 27-444, 3141 Chestnut Street, Philadelphia, 19104 PA, USAAlexander J Vega - Department of Chemistry and Biochemistry, University of Delaware, 036 Brown Laboratories, Newark, 19716 DE, USAMichele Marcolongo - Department of Materials Science and Engineering, Drexel University, LeBow 27-444, 3141 Chestnut Street, Philadelphia, 19104 PA, USATatyana Polenova - Department of Chemistry and Biochemistry, University of Delaware, 036 Brown Laboratories, Newark, 19716 DE, USA
- Publication Details
- Journal of magnetic resonance (1997), Vol.195(1)
- Publisher
- Elsevier
- Resource Type
- Journal article
- Language
- English
- Identifiers
- 991014878141604721
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- Collaboration types
- Domestic collaboration
- Web of Science research areas
- Biochemical Research Methods
- Physics, Atomic, Molecular & Chemical
- Spectroscopy