Journal article
3-D Simulation of Electroosmotic Injection and Migration in Microchannels: Effects of Non-Rectangular Cross Section
Separation science and technology, v 46(2), pp 195-204
28 Dec 2010
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
A numerical study of the 3-D characteristics of electroosmotic injection and migration of sample species in microchip capillary electrophoresis systems is reported. In particular, the effect of a non-rectangular cross section commonly found in isotropically-etched microchannels is thoroughly investigated through 3-D numerical simulations. A non-rectangular cross section resulted in a vertically non-uniform sample plug during the loading stage. Conventional 2-D simulation approach can result in up to 40% errors in the calculation of injection qualities. It was also found that the 2-D simulation using a proper channel width has a good agreement with the 3-D simulation data.
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Details
- Title
- 3-D Simulation of Electroosmotic Injection and Migration in Microchannels: Effects of Non-Rectangular Cross Section
- Creators
- Doh-Hyoung Lee - Mechanical Engineering and Mechanics Department, Drexel UniversityBakhtier Farouk - Mechanical Engineering and Mechanics Department, Drexel UniversityH.-S Noh - Mechanical Engineering and Mechanics Department, Drexel University
- Publication Details
- Separation science and technology, v 46(2), pp 195-204
- Publisher
- Taylor & Francis Group
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Mechanical Engineering and Mechanics
- Web of Science ID
- WOS:000286822700002
- Scopus ID
- 2-s2.0-78751605653
- Other Identifier
- 991014878014404721
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InCites Highlights
Data related to this publication, from InCites Benchmarking & Analytics tool:
- Web of Science research areas
- Chemistry, Multidisciplinary
- Engineering, Chemical