Journal article
3-mercaptopropyltrimethoxysilane as insulating coating and surface for protein immobilization for piezoelectric microcantilever sensors
Drexel University. College of Engineering. Department of Materials Science and Engineering. Faculty Research and Publications
09 Jul 2007
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
We have examined coating PbMg1/3Nb2/3O3 0.63– PbTiO3 0.37 PMN-PT /tin and lead zirconate titanate PZT /glass piezoelectric microcantilever sensor PEMS with 3-mercaptopropyltrimethoxysilane MPS by a simple solution method to electrically insulate the PEMS for in-water applications. In contrast to earlier methytrimethoxysilane insulation coating, the MPS coating also facilitated receptor immobilization on the sensor surface via bonding of its sulhydryl group to a bifunctional linker, sulfosuccinimidyl-4- N-maleimidomethyl cyclohexane-1-carboxylate. We showed that a MPS coating of 21 nm in thickness is sufficient to electrically insulate and provide immobilization surface to the PEMS for in-liquid electrical self-excitation and self-sensing. The in-phosphate buffered saline solution resonance spectra were stable with Q values ranging from 41 to 55. The mass detection sensitivities were determined to be 5 10−11 and 8 10−12 g/Hz for the MPS-insulated PZT-glass and PMN-PT/tin PEMSs, respectively.
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Details
- Title
- 3-mercaptopropyltrimethoxysilane as insulating coating and surface for protein immobilization for piezoelectric microcantilever sensors
- Creators
- Joseph A. Capobianco (Author) - Drexel University (1970-)Wan Y. Shih (Author) - Drexel University (1970-)Wei-Heng Shih (Author) - Drexel University (1970-)
- Publication Details
- Drexel University. College of Engineering. Department of Materials Science and Engineering. Faculty Research and Publications
- Publisher
- American Institute of Physics (AIP)
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Materials Science and Engineering; College of Engineering
- Web of Science ID
- WOS:000246073500055
- Scopus ID
- 2-s2.0-34247560868
- Other Identifier
- 991014632655204721
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Data related to this publication, from InCites Benchmarking & Analytics tool:
- Web of Science research areas
- Instruments & Instrumentation
- Physics, Applied