Logo image
Back
339 The Use of an Autologous Cell Harvesting and Processing Device in Two Burn Patients at an Urban Pediatric Burn Center
Journal article   Peer reviewed

339 The Use of an Autologous Cell Harvesting and Processing Device in Two Burn Patients at an Urban Pediatric Burn Center

P M Glat, A D Nanassy, B A Burkey, A C Misra, L K Meyer, L Gates and W J Davis III
Journal of burn care & research, v 40(Supplement_1), pp S146-S147
09 Mar 2019
DOI: https://doi.org/10.1093/jbcr/irz013.250

Abstract

Abstract Introduction Autologous cell suspension (ACS) is utilized in individuals with large burns to enhance skin regeneration, thus decreasing risk of infection, expediting the time to wound closure, and improving outcomes. Currently, ACS can be used as a treatment of life-threatening wounds requiring closure in patients who lack adequate available skin to harvest for conventional grafting. Methods The first patient was a 4 year old female with 32% total body surface area full and partial-thickness burn injuries. The patient was injured when a crock-pot of hot grease spilled on her head, trunk, flank, arms, thighs, and feet. The second patient was an 18 month old female with 21% total body surface area full and partial-thickness burn injuries to the bilateral lower extremities from being submerged her in hot bathwater by a caretaker. Both pediatric patients were treated with ACS. Results The first patient’s treatment sites had reached 95-100% epithelization and all donor sites had reached 100% epithelization 14 post-ACS treatment. The first patient was discharged to a rehabilitation center 19 days post-ACS treatment. Neither patient required additional surgical interventions. The second patient’s donor sites had reached 100% epithelization and treatment areas were estimated to be healed between 70-85% 14 days post-ACS treatment. The second patient was discharged home 22 days post-ACS treatment. Neither patient experienced any unexpected treatment related adverse events. Conclusions The cases of these pediatric burn patients support the existing literature that suggests utilizing ACS to treat burn injuries can help decrease surgical procedures and expedite healing. Applicability of Research to Practice ACS is an alternative to cultured epithelial autografts and can be used as an adjunct to traditional skin grafts, biologic or synthetic skin substitutes that eliminates the waiting time of growing epithelial cells at an off-site laboratory. The literature suggests that ACS may help to decrease the number of surgical interventions performed, pain, and scarring by expediting healing and minimizing donor site areas in pediatric burn patients.

Metrics

5 Record Views

Details

Logo image