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3D Numerical modeling and its experimental verifications for an inhomogeneous head phantom using broadband fNIR system
Journal article   Peer reviewed

3D Numerical modeling and its experimental verifications for an inhomogeneous head phantom using broadband fNIR system

E Sultan, K Pourrezaei, A Ghandjbakhche and A.S Daryoush
International journal for numerical methods in biomedical engineering, v 30(3), pp 353-364
Mar 2014
PMID: 24259456

Abstract

DE PDW IL optical receiver Rx IP FEM TD CW optical transmitter Tx VCSEL TBI tri‐wavelength COMSOL fNIR FD
SUMMARYModeling behavior of broadband (30–1000 MHz) frequency modulated near infrared photons through a multilayer phantom is of interest to optical bio‐imaging research. Photon dynamics in phantom are predicted using three‐dimension (3D) finite element numerical simulation and are related to the measured insertion loss and phase for a given human head geometry in this paper based on three layers of phantom each with distinct optical parameter properties. Simulation and experimental results are achieved for single, two, and three layers solid phantoms using COMSOL (COMSOL AB, Tegnérgatan 23, SE‐111 40, Stockholm, Sweden) (for FEM) simulation and custom‐designed broadband free space optical transmitter (Tx) and receiver (Rx) modules that are developed for photon migration at wavelengths of 680, 795, and 850 nm. Standard error is used to compute error between two‐dimension and 3D FE modeling along with experimental results by fitting experimental data to the functional form of afrequency+b. Error results are shown at narrowband and broadband frequency modulation. Confidence in numerical modeling of the photonic behavior using 3D FEM for human head has been established here by comparing the reflection mode's experimental results with the predictions made by COMSOL for known commercial solid brain phantoms. Copyright © 2013 John Wiley & Sons, Ltd. Modeling behavior of broadband (30‐1000 MHZ) frequency modulated near infrared photons through a multilayer phantom is of interest to optical bio‐imaging research. Photon dynamics in phantom are predicted using 3D finite element numerical simulation and are related to the experimentally measured insertion loss and phase for a given human head geometry in this paper based on three layers of phantom each with distinct optical parameter properties.

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Collaboration types
Domestic collaboration
Web of Science research areas
Engineering, Biomedical
Mathematical & Computational Biology
Mathematics, Interdisciplinary Applications
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