Journal article
50 Years Ago in The Journal of Pediatrics: The Pathologic Behavior of Adenoviruses
The Journal of pediatrics, v 237, pp 23-23
01 Oct 2021
PMID: 34563322
Abstract
The eloquence of the study by Simila et al of 29 patients with type 7 adenovirus pneumonia hospitalized at the University of Oulu, Oulu, Finland during 1967 and 1968 was remarkable then for the large number of cases, and now for its uncommonly thorough investigations. Cases of 17 children hospitalized for bacterial and viral pneumonia over the same period who were proved not to have acute adenovirus infection served as a comparison group. Inoculation of throat, nasal, and rectal specimens from most patients in both groups onto primary monkey kidney cells for virus isolation as well as comparison of acute and convalescent serum for adenovirus 7 complement fixing antibody permitted precise distinction of cases and controls. Careful recording of prior histories and measurement of serum immunoglobulin and α1-antitrypsin levels provided evidence that those with adenovirus 7 pneumonia were previously healthy children. Careful follow-up at 1-3 years of age permitted the conclusion that adenovirus 7 pneumonia was associated with chronic bronchopulmonary sequelae (lung fibrosis in 2 patients and bronchiectasis in 2 patients).
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Details
- Title
- 50 Years Ago in The Journal of Pediatrics: The Pathologic Behavior of Adenoviruses
- Creators
- Sarah S. Long - Drexel University
- Publication Details
- The Journal of pediatrics, v 237, pp 23-23
- Publisher
- Elsevier
- Number of pages
- 1
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Pediatrics
- Web of Science ID
- WOS:000699805300006
- Scopus ID
- 2-s2.0-85115030077
- Other Identifier
- 991019335317704721
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- Web of Science research areas
- Pediatrics