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Journal article
A 73-Year-Old Man with an Incidental Diagnosis of Deltoid Intramuscular Myxoma Following a History of Trauma
The American journal of case reports, v 23, 936654
08 Aug 2022
PMID: 35934869
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Objective: Rare disease
Background: Intramuscular myxomas are rare and benign soft-tissue tumors of uncertain differentiation. Predisposing or precipitating factors have not yet been reported. Activating mutation in GNAS (exons 8 and 9) is detected in >90% of sporadic cases. The role of chronic myopathy, tendinopathy, or trauma to muscles in the etiology of these neoplasms is not known. We report an unusual case of a deltoid mass found following longstanding rotator cuff tendinopathy and a recent fall, later confirmed to be an intramuscular myxoma on biopsy.
Case Report: A 73-year-old man with a 5-year history of left shoulder pain and rotator cuff tear presented with intractable pain in his left shoulder after a recent fall at home. Physical examination was suggestive of a rotator cuff injury and magnetic resonance imaging (MRI) of the left shoulder revealed a 2.7x2.5x3.7cm T1 hypo-and T2 hyperin-tense oblong mass-like signal abnormality with heterogeneous, predominantly peripheral enhancement within the deltoid muscle concerning for a malignant mass. Surgical resection was carried out along with left reverse total shoulder replacement, and histopathology revealed findings consistent with an intramuscular myxoma.
Conclusions: Intramuscular myxomas are rare, benign tumors. This case report presents one such myxoma incidentally found in a patient with longstanding rotator cuff tendinopathy and a recent fall. Although this co-occurrence is likely incidental, further research and case series review of similar presentations may influence postulations of the pathophysiology of myxomas.
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Details
- Title
- A 73-Year-Old Man with an Incidental Diagnosis of Deltoid Intramuscular Myxoma Following a History of Trauma
- Creators
- Christian Akem Dimala - Reading HospitalIbiyemi Oke - Reading Hosp, Dept Med, Tower Hlth Syst, W Reading, PA 19610 USAFikru Merechi - Reading HospitalRyan P. Zimmerman - Drexel University, College of Medicine
- Publication Details
- The American journal of case reports, v 23, 936654
- Publisher
- Int Scientific Information, Inc
- Number of pages
- 5
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- College of Medicine
- Web of Science ID
- WOS:000841452400001
- Scopus ID
- 2-s2.0-85135552339
- Other Identifier
- 991021861202204721
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Data related to this publication, from InCites Benchmarking & Analytics tool:
- Web of Science research areas
- Radiology, Nuclear Medicine & Medical Imaging