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Journal article
A Bivariate Twin Study of Regional Brain Volumes and Verbal and Nonverbal Intellectual Skills During Childhood and Adolescence
Behavior genetics, v 40(2), pp 125-134
01 Mar 2010
PMID: 20112131
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Twin studies indicate that both intelligence and brain structure are moderately to highly heritable. Recent bivariate studies of adult twins also suggest that intelligence and brain morphometry are influenced by shared genetic factors. The current study examines shared genetic and environmental factors between brain morphometry and intelligence in a sample of children and adolescents (twins, twin siblings, and singletons; n = 649, ages 4-19). To extend previous studies, brain morphometric data were parsed into subregions (lobar gray/white matter volumes, caudate nucleus, lateral ventricles) and intelligence into verbal and nonverbal skills (Wechsler Vocabulary and Block Design subtests). Phenotypic relationships between brain volumes and intelligence were small. Verbal skills shared unique environmental effects with gray matter volumes while nonverbal skills shared genetic effects with both global and regional gray and white matter. These results suggest that distinct mechanisms contribute to the small phenotypic relationships between brain volumes and verbal versus nonverbal intelligence.
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Details
- Title
- A Bivariate Twin Study of Regional Brain Volumes and Verbal and Nonverbal Intellectual Skills During Childhood and Adolescence
- Creators
- Gregory L. Wallace - National Institutes of HealthNancy Raitano Lee - National Institutes of HealthElizabeth C. Prom-Wormley - Virginia Commonwealth UniversitySarah E. Medland - Virginia Commonwealth Univ, Virginia Inst Psychiat & Behav Genet, Richmond, VA USARhoshel K. Lenroot - National Institutes of HealthLiv S. Clasen - National Institutes of HealthJames E. Schmitt - Virginia Commonwealth UniversityMichael C. Neale - Virginia Commonwealth UniversityJay N. Giedd - National Institutes of Health
- Publication Details
- Behavior genetics, v 40(2), pp 125-134
- Publisher
- Springer Nature
- Number of pages
- 10
- Grant note
- MH-20030 / NIH; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA 443036; SEM / NHMRC Australia, Sidney; National Health and Medical Research Council (NHMRC) of Australia National Institute of Mental Health; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Institute of Mental Health (NIMH) T32MH020030; ZIAMH002794 / NATIONAL INSTITUTE OF MENTAL HEALTH; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Institute of Mental Health (NIMH)
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Psychological and Brain Sciences (Psychology)
- Web of Science ID
- WOS:000274964000003
- Scopus ID
- 2-s2.0-77949267592
- Other Identifier
- 991019296757504721
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- Collaboration types
- Domestic collaboration
- International collaboration
- Web of Science research areas
- Behavioral Sciences
- Genetics & Heredity
- Psychology, Multidisciplinary