Journal article
A Facile Strategy for Preparing Tough, Self-Healing Double-Network Hyaluronic Acid Hydrogels Inspired by Mussel Cuticles
Macromolecular materials and engineering, v 304(4), pp 1-7
01 Apr 2019
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Compared with hydrogel-like biological tissues such as cartilage, muscles, and blood vessels, current hyaluronic acid hydrogels often suffer from poor toughness and limited self-healing properties. Herein, a facile and generalizable strategy inspired by mussel cuticles is presented to fabricate tough and self-healing double-network hyaluronic acid hydrogels. These hydrogels are composed of ductile, reversible Fe3+-catechol interaction primary networks, and secondarily formed brittle, irreversible covalent networks. Based on this design strategy, the hyaluronic acid hydrogels are demonstrated to exhibit reinforced mechanical strength while maintaining a rapid self-healing property. In addition, by simply regulating pH or UV irradiation time, the mechanical properties of the hydrogels can be regulated conveniently through variations between the primary and secondary networks.
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Details
- Title
- A Facile Strategy for Preparing Tough, Self-Healing Double-Network Hyaluronic Acid Hydrogels Inspired by Mussel Cuticles
- Creators
- Zhongwei Guo - Tsinghua–Berkeley Shenzhen InstituteShengli Mi - Tsinghua UniversityWei Sun - Tsinghua Berkeley Shenzhen Inst, Precis Med & Healthcare Res Ctr, Shenzhen 518055, Peoples R China
- Publication Details
- Macromolecular materials and engineering, v 304(4), pp 1-7
- Publisher
- Wiley
- Number of pages
- 7
- Grant note
- JCYJ20170412101508433; JCYJ20160509154841455; JCYJ20160509154951210 / projects of fundamental research of Shenzhen
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Mechanical Engineering and Mechanics
- Web of Science ID
- WOS:000464437200023
- Scopus ID
- 2-s2.0-85061289919
- Other Identifier
- 991019167571104721
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- Collaboration types
- Domestic collaboration
- International collaboration
- Web of Science research areas
- Materials Science, Multidisciplinary
- Polymer Science