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A Novel Bayesian Spatio‐Temporal Surveillance Metric to Predict Emerging Infectious Disease Areas of High Disease Risk
Journal article   Peer reviewed

A Novel Bayesian Spatio‐Temporal Surveillance Metric to Predict Emerging Infectious Disease Areas of High Disease Risk

Joanne Kim, Andrew B. Lawson, Brian Neelon, Jeffrey E. Korte, Jan M. Eberth and Gerardo Chowell
Statistics in medicine, v 43(28), pp 5300-5315
10 Oct 2024
PMID: 39385731
url
https://doi.org/10.1002/sim.10227View
Published, Version of Record (VoR) Restricted

Abstract

Bayesian infectious disease prediction spatio-temporal model Public Health
ABSTRACT Identification of areas of high disease risk has been one of the top goals for infectious disease public health surveillance. Accurate prediction of these regions leads to effective resource allocation and faster intervention. This paper proposes a novel prediction surveillance metric based on a Bayesian spatio‐temporal model for infectious disease outbreaks. Exceedance probability, which has been commonly used for cluster detection in statistical epidemiology, was extended to predict areas of high risk. The proposed metric consists of three components: the area's risk profile, temporal risk trend, and spatial neighborhood influence. We also introduce a weighting scheme to balance these three components, which accommodates the characteristics of the infectious disease outbreak, spatial properties, and disease trends. Thorough simulation studies were conducted to identify the optimal weighting scheme and evaluate the performance of the proposed prediction surveillance metric. Results indicate that the area's own risk and the neighborhood influence play an important role in making a highly sensitive metric, and the risk trend term is important for the specificity and accuracy of prediction. The proposed prediction metric was applied to the COVID‐19 case data of South Carolina from March 12, 2020, and the subsequent 30 weeks of data.

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Collaboration types
Domestic collaboration
International collaboration
Web of Science research areas
Mathematical & Computational Biology
Medical Informatics
Medicine, Research & Experimental
Public, Environmental & Occupational Health
Statistics & Probability
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