Journal article
A Population-Based Study of Intracerebral Hemorrhage Survivors’ Outcomes
Journal of stroke and cerebrovascular diseases, v 28(1), pp 49-55
Jan 2019
PMID: 30274873
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
We evaluated 3-month neurologic, functional, cognitive, and quality of life (QOL) outcomes in intracerebral hemorrhage (ICH) overall, and by sex and ethnicity in a population-based study.
Spontaneous ICH patients were identified from the Brain Attack Surveillance in Corpus Christi project (November 2008 to December 2013). Outcomes included neurologic (National Institutes of Health Stroke Scale: range 0-42), functional (activities of daily living/instrumental activities of daily living score: range 1-4, higher worse), cognitive (Modified Mini-Mental State Examination [3MSE]: range 0-100), and QOL (short-form stroke-specific QOL scale: range 0-5, higher better). Ethnic and sex differences were assessed with Tobit regression adjusted for age, sex, or ethnicity, and presenting Glasgow coma scale.
A total of 245 patients completed baseline interviews, with 103 (42%) dying prior to follow-up, leaving 142 eligible for outcome assessment. Three-month follow-up was completed in 100 (neurologic), 107 (functional), 79 (cognitive), and 83 (QOL) participants. Median age was 66 years (interquartile range 58.0-77.0). Cognitive outcomes were worse in Mexican Americans (MA) compared to non-Hispanic whites (NHW) after multivariable adjustment (MA scoring 13.3 3MSE points lower than NHW [95% confidence interval: 5.8, 20.7; P = .0005]). There was no difference by sex or ethnicity in neurological, functional, or QOL outcomes, and no sex differences in cognitive outcomes.
In this population-based study, worse cognitive outcomes were found in MAs compared with NHW. There were no differences between neurologic, functional, and QOL outcomes in ICH survivors based on sex or ethnicity.
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Details
- Title
- A Population-Based Study of Intracerebral Hemorrhage Survivors’ Outcomes
- Creators
- Julius Griauzde - Department of Radiology, Michigan Medicine, Ann Arbor, MichiganLynda D Lisabeth - Stroke Program, Department of Neurology, Michigan Medicine, Ann Arbor, MichiganChengwei Li - Stroke Program, Department of Neurology, Michigan Medicine, Ann Arbor, MichiganBrisa N Sanchez - Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, MichiganErin Case - Stroke Program, Department of Neurology, Michigan Medicine, Ann Arbor, MichiganNelda M Garcia - Stroke Program, Department of Neurology, Michigan Medicine, Ann Arbor, MichiganLewis B Morgenstern - Stroke Program, Department of Neurology, Michigan Medicine, Ann Arbor, MichiganDarin B Zahuranec - Stroke Program, Department of Neurology, Michigan Medicine, Ann Arbor, Michigan
- Publication Details
- Journal of stroke and cerebrovascular diseases, v 28(1), pp 49-55
- Publisher
- Elsevier
- Grant note
- R01NS38916; K23AG038731; U10NS086526; R01NS091112; R01NS070941 / National Institutes of Health (http://dx.doi.org/10.13039/100000002)
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Epidemiology and Biostatistics
- Web of Science ID
- WOS:000452320600009
- Scopus ID
- 2-s2.0-85054058518
- Other Identifier
- 991014878025004721
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InCites Highlights
Data related to this publication, from InCites Benchmarking & Analytics tool:
- Web of Science research areas
- Neurosciences
- Peripheral Vascular Disease