Journal article
A Randomized Pilot Study of Near Activities Versus Non-Near Activities During Patching Therapy for Amblyopia
Journal of AAPOS, v 9(2), pp 129-136
01 Apr 2005
PMID: 15838439
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Background:
To plan a future randomized clinical trial, we conducted a pilot study to determine whether children randomized to near or non-near activities would perform prescribed activities. A secondary aim was to obtain a preliminary estimate of the effect of near versus non-near activities on amblyopic eye visual acuity, when combined with 2 hours of daily patching.
Methods:
Sixty-four children, 3 to less than 7 years of age, with anisometropic, strabismic, or combined amblyopia (20/40 to 20/400) were randomly assigned to receive either 2 hours of daily patching
with near activities or 2 hours of daily patching
without near activities. Parents completed daily calendars for 4 weeks recording the activities performed while patched and received a weekly telephone call in which they were asked to describe the activities performed during the previous 2 hours of patching. Visual acuity was assessed at 4 weeks.
Results:
The children assigned to near visual activities performed more near activities than those assigned to non-near activities (by calendars, mean 1.6 ± 0.5 hours versus 0.2 ± 0.2 hours daily,
P < 0.001; by telephone interviews, 1.6 ± 0.4 hours versus 0.4 ± 0.5 hours daily,
P < 0.001). After 4 weeks of treatment, there was a suggestion of greater improvement in amblyopic eye visual acuity in those assigned to near visual activities (mean 2.6 lines versus 1.6 lines,
P = 0.07). The treatment group difference in visual acuity was present for patients with severe amblyopia but not moderate amblyopia.
Conclusions:
Children patched and instructed to perform near activities for amblyopia spent more time performing those near activities than children who were instructed to perform non-near activities. Our results suggest that performing near activities while patched may be beneficial in treating amblyopia. Based on our data, a formal randomized amblyopia treatment trial of patching with and without near activities is both feasible and desirable.
Metrics
Details
- Title
- A Randomized Pilot Study of Near Activities Versus Non-Near Activities During Patching Therapy for Amblyopia
- Creators
- Jonathan M. Holmes - Jaeb Center for Health ResearchThe Pediatric Eye Disease Investigator GroupMitchell Scheiman - Pennsylvania College of Optometry (PCO)
- Publication Details
- Journal of AAPOS, v 9(2), pp 129-136
- Publisher
- Mosby, Inc
- Number of pages
- 8
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Pennsylvania College of Optometry (PCO)
- Web of Science ID
- WOS:000228808400006
- Scopus ID
- 2-s2.0-17444367711
- Other Identifier
- 991021900190404721
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InCites Highlights
Data related to this publication, from InCites Benchmarking & Analytics tool:
- Web of Science research areas
- Ophthalmology
- Pediatrics