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A Review of Evidence-Based Care of Symptomatic Trichomoniasis and Asymptomatic Trichomonas vaginalis Infections
Journal article   Open access   Peer reviewed

A Review of Evidence-Based Care of Symptomatic Trichomoniasis and Asymptomatic Trichomonas vaginalis Infections

Elissa Meites, Charlotte A Gaydos, Marcia M Hobbs, Patricia Kissinger, Paul Nyirjesy, Jane R Schwebke, W Evan Secor, Jack D Sobel and Kimberly A Workowski
Clinical infectious diseases, v 61 Suppl 8(suppl 8), pp S837-S848
15 Dec 2015
DOI: https://doi.org/10.1093/cid/civ738
PMID: 26602621
Featured in Collection :   UN Sustainable Development Goals @ Drexel
url
https://academic.oup.com/cid/article-pdf/61/suppl_8/S837/20914710/civ738.pdfView
Published, Version of Record (VoR) Open
url
https://doi.org/10.1093/cid/civ738View
Published, Version of Record (VoR) Open

Abstract

Antiprotozoal Agents - therapeutic use Asymptomatic Infections - epidemiology Centers for Disease Control and Prevention (U.S.) Drug Resistance, Bacterial Evidence-Based Medicine Female HIV Infections - complications HIV Infections - drug therapy Humans Male Point-of-Care Systems Practice Guidelines as Topic Pregnancy Pregnancy Complications, Infectious - drug therapy Pregnancy Complications, Infectious - microbiology Risk Factors Sexually Transmitted Diseases - diagnosis Sexually Transmitted Diseases - drug therapy Sexually Transmitted Diseases - microbiology Trichomonas Infections - drug therapy Trichomonas vaginalis - drug effects Trichomonas vaginalis - genetics Trichomonas Vaginitis - drug therapy Trichomonas Vaginitis - epidemiology Trichomonas Vaginitis - microbiology United States - epidemiology
Trichomonas vaginalis is the most prevalent nonviral sexually transmitted infection, affecting an estimated 3.7 million women and men in the United States. Health disparities are prominent in the epidemiology of this infection, which affects 11% of women aged ≥40 years and a disproportionately high percentage of black women. Particularly high prevalences have been identified among sexually transmitted disease (STD) clinic patients and incarcerated individuals. This article reviews and updates scientific evidence in key topic areas used for the development of the 2015 STD Treatment Guidelines published by the Centers for Disease Control and Prevention. Current evidence is presented regarding conditions associated with Trichomonas vaginalis infection, including human immunodeficiency virus (HIV) and pregnancy complications such as preterm birth. Nucleic acid amplification tests and point-of-care tests are newly available diagnostic methods that can be conducted on a variety of specimens, potentially allowing highly sensitive testing and screening of both women and men at risk for infection. Usually, trichomoniasis can be cured with single-dose therapy of an appropriate nitroimidazole antibiotic, but women who are also infected with HIV should receive therapy for 7 days. Antimicrobial resistance is an emerging concern.

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13 Record Views
94 citations in Web of Science
126 citations in Scopus

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UN Sustainable Development Goals (SDGs)

This publication has contributed to the advancement of the following goals:

#3 Good Health and Well-Being
#5 Gender Equality

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Collaboration types
Domestic collaboration
Web of Science research areas
Immunology
Infectious Diseases
Microbiology
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