Files and links (1)
Published, Version of Record (VoR)CC BY V4.0, Open
Journal article
A combination intervention addressing sexual risk-taking behaviors among vulnerable women in Uganda: study protocol for a cluster randomized clinical trial
BMC women's health, Vol.19(1), pp.111-111
17 Aug 2019
PMCID: PMC6697981
PMID: 31419968
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Sub-Saharan Africa (SSA) has the highest number of people living with HIV/AIDS, with Nigeria, South Africa, and Uganda accounting for 48% of new infections. A systematic review of the HIV burden among women engaged in sex work (WESW) in 50 low- and middle-income countries found that they had increased odds of HIV infection relative to the general female population. Social structural factors, such as the sex work environment, violence, stigma, cultural issues, and criminalization of sex work are critical in shaping sexually transmitted infection (STI)/HIV risks among WESW and their clients in Uganda. Poverty is the most commonly cited reason for involvement in sex work in SSA. Against this backdrop, this study protocol describes a randomized controlled trial (RCT) that tests the impact of adding economic empowerment to traditional HIV risk reduction (HIVRR) to reduce new incidence of STIs and HIV among WESW in Rakai and the greater Masaka regions in Uganda.
This three-arm RCT will evaluate the efficacy of adding savings, financial literacy and vocational training/mentorship to traditional HIVRR on reducing new incidence of STI infections among 990 WESW across 33 hotspots. The three arms (n = 330 each) are: 1) Control group: only HIVRR versus 2) Treatment group 1: HIVRR plus Savings plus Financial Literacy (HIVRR + S + FL); and 3) Treatment group 2: HIVRR plus S plus FL plus Vocational Skills Training and Mentorship (V) (HIVRR + S + FL + V). Data will be collected at baseline (pre-test), 6, 12, 18 and 24-months post-intervention initiation. This study will use an embedded experimental mixed methods design where qualitative data will be collected post-intervention across all conditions to explore participant experiences.
When WESW have access to more capital and/or alternative forms of employment and start earning formal income outside of sex work, they may be better able to improve their skills and employability for professional advancement, thereby reducing their STI/HIV risk. The study findings may advance our understanding of how best to implement gender-specific HIV prevention globally, engaging women across the HIV treatment cascade. Further, results will provide evidence for the intervention's efficacy to reduce STIs and inform implementation sustainability, including costs and cost-effectiveness.
ClinicalTrials.gov , ID: NCT03583541 .
Metrics
9 Record Views
Details
- Title
- A combination intervention addressing sexual risk-taking behaviors among vulnerable women in Uganda: study protocol for a cluster randomized clinical trial
- Creators
- Fred M Ssewamala - Washington University in St. LouisOzge Sensoy Bahar - Brown School, Washington University in St. Louis, Campus Box 1196, One Brookings Drive, St. Louis, MO, 63130, USAYesim Tozan - College of Global Public Health, New York University, New York City, USAProscovia Nabunya - Washington University in St. LouisLarissa Jennings Mayo-Wilson - Indiana UniversityJoshua Kiyingi - National Center For Child Health and DevelopmentJoseph Kagaayi - Rakai Health Sciences ProgramScarlett Bellamy - Drexel UniversityMary M McKay - Washington University in St. LouisSusan S Witte - Columbia University
- Publication Details
- BMC women's health, Vol.19(1), pp.111-111
- Publisher
- Springer BMC
- Grant note
- R25 MH118935 / NIMH NIH HHS R25 HD045810 / NICHD NIH HHS P50 MH113662 / NIMH NIH HHS R01 MH116768 / NIMH NIH HHS R01 HD074949 / NICHD NIH HHS R25 MH067127 / NIMH NIH HHS
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Epidemiology and Biostatistics
- Identifiers
- 991019167620804721
UN Sustainable Development Goals (SDGs)
This output has contributed to the advancement of the following goals:
InCites Highlights
These are selected metrics from InCites Benchmarking & Analytics tool, related to this output
- Collaboration types
- Domestic collaboration
- International collaboration
- Web of Science research areas
- Obstetrics & Gynecology
- Public, Environmental & Occupational Health